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1 (Table of Contents) - 2-3-4-5-6
Table II: Compounds tested and
found not to cross-react with the test as a 1 mg/ml concentration
in urine.
The following compounds do not cross-react with Amphetamine:
Acetaminophen
Actylsalicylic Acid
Amikacin
Amitriptyline
Ampicillin
Arterenol
Aspartame
Atropine Sulfate
Benzoic Acid
Benzoylecgonine HCl
Caffeine
Chlorpheniramine
Chlorpropmazine HCl
Cimetidine
Codeine
Deoxyephedrine
Dextromethorphan
Diazepam
Diethylpropion |
Diphenylhydantoin
Doxylamine
Ecgonine HCl
Ecgonine Methyl Ester
Glucose
Histamine
Hydrocodone
Hydromorphone
Indomathacin
Ketoprofen
Levorphanol
D - 9 THC
11-nor-D-9-carboxy-THC-9-COOH
Meperidine
Methylphenidate
Methadone
Methaqualone
Morp. Glucuronide
Morphine Sulfate
Oxazepam |
Oxycodone
Pendimetrazine
Penicillin G
Pentobarbital
d-Propoxyphene
Hydrochlorthiazide
Propanol
Phencyclidine
Phenobarbital
Phentermine
Phenylpropanolamine
L-Phenylephrine
Quinine
Ranitidine
Sodium Salicylate
Tryptophan
Tetracycline
Tetrahydrozoline
Theophylline
Thioridazine
Triflouperazine |
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The following compounds do not
cross-react with Marijuana:
Acetaminophen
4-Acetamidophenol
Acetylsalicyclic acid
Amikacin
Ampicillin
d,l-Amphetamine
Amitriptyline
Arterenol
Aspartame
Atropine sulfate
Benzoic Acid
Benzoylecgonine
Caffeine
Camphor
Chloroquine
Chlorpheniramine
Chlorpromazine HCl
Cocaine Hydrochloride
Cocaine
Cimetidine
Cortisone
Deoxyepinophrine
Dextromethorphan
Diazepam
Digitoxin |
Digoxin
Ecgonine Hydrochloride
Ecgonine Methyl Ester
Ephedrine
Epinephrine
Gentisic acid
Glucose
Guaiacol
Histamine
Hydrochlorothiazide
Hydrocodone Hydromorphone
Homatropine
Imipramine
Isoproterenol
Ketamine
Lidocaine
d-Phencyclidine (PCP)
Meperidine
Methadone
Methaqualone
Methylpehnidate
Morphine glucuronide
Morphine sulfate
Morphine |
Naloxone
Neomycin
Niacinamide
Oxazepam
Perphenazine
Penicillin G
Phencyclidine
Phenobarbital
Phenylethylamine-a
Phenylpropanolamine
Promethazine
Pseudophedrine
Rantidine
Salycyclic acid
Secobarbital
Tetracycline
Tetrahydrozoline
Theophylline
Thiridazine
Triflouperazine
Tryptophan |
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The following compounds do not
cross-react with Cocaine:
Acetaminophen
Actylsalicylic Acid
Amikacin
Amitriptyline
Ampicillin
Arterenol
Aspartame
Atropine Sulfate
Benzoic Acid
Benzoylecgonine HCl
Caffeine
Chlorpheniramine
Chlorpropmazine HCl
Cimetidine
Codeine
Deoxyephedrine
Dextromethorphan
Diazepam
Hydromorphone
Indomathacin
Ketoprofen
Levorphanol
D -9-THC |
Diethylpropion
Dephenylhydantoin
Doxylamine
Ecgonine HCl
Ecgonine Methyl Ester
Glucose
Histamine
Hydrocodone
11-nor-D -9-carboxy-THC-9-COOH
Meperidine
Methylphenidate
Methadone
Methaqualone
Morp. Glucuronide
Morphine Sulfate
Oxazepam
Oxycodone
Pendimetrazine
Penicillin G
Pentobarbital
d-Propoxyphene Hydro-
chlorothiazide
Propanol |
Phencyclidine
Phenobarbital
Phentermine
Phenylpropanolamine
L-Phenylephrine
Quinine
Ranitidine
Sodium Salicylate
Tryptophan
Tetrahydrozoline
Theophylline
Thioridazine
Trifluoperazine |
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The following compounds do not
cross-react with Opiates:
Acetaminophen
Acetylsalicylic Acid
Amikacin
Amitriptyline
Ampicillin
Arterenol
Aspartame
Atropine Sulfate
Benzoic Acid
Benzoylecgonine HCl
Caffeine
Chlorpheniramine
Chlorpropmazine HCl
Cimetidine
Deoxyephedrine
Dextromethorphan
Diazepam
Diethylpropion |
Diphenylhydantoin
Doxylamine
Ecgonine HCl
Ecgonine Methyl Ester
Glucose
Histamine
Indomathacin
Ketoprofen
Levorphanol
D - 9 THC
11-nor-D-9-carboxy-THC-9-COOH
Methylphenidate
Methadone
Methaqualone
Morphine Sulfate
Oxazepam
Pendimetrazine
Penicillin G |
Pentobarbital
d-Propoxyphene-
Hydrochlorothiazide
Propanol
Phencyclidine
Phenobarbital
Phentermine
Phenylpropanolamine
L-Phenylephrine
Quinine
Sodium Salicylate
Tryptophan
Tetracycline
Tetrahydrozoline
Theophylline
Thioridazine
Trifluoperazine |
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The following compounds do not
cross-react with Phencyclidine (PCP):
Acetylsalicylic
Acid
Amikacin
Amitriptyline
Ampicillan
Arterenol
Aspartame
Atropine Sulfate
Benzoic Acid
Benzoylecgonine HCl
Caffeine
Chlorpheniramine
Chlorpropmazine HCl
Cimetidine
Codeine
Deoxyephedrine
Dextromethorphan
Diazepam
Diethylpropion
Dephenylhydantoin
Doxylamine |
Ecgonine HCl
Ecgonine Methyl Ester
Glucose
Histamine
Hydrocodone
Hydromorphone
Indomathacin
Ketoprofen
Levorphanol
D 9-TC
11-nor-D-9-carboxy-THC-9-COOH
Meperdine
Methylphenidate
Methadone
Methaqualone
Morp. Glucuronide
Morphine Sulfate
Oxazepam
Oxycodone
Pendimetrazine |
Penicillin
G
Pentobarbital
d-Propoxyphene-
Hydrochlorthiazide
Propanol
Phencyclidine
Phenobarbital
Phentermine
Phenylpropanolamine
L-Phenylephrine
Quinine
Ranitidine
Sodium Salicylate
Tryptophan
Tetracycline
Tetrahydrozoline
Theophylline
Thioridazine
Triflouperazine |
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- Accuracy: The accuracy of
the DrugCheck 5 was first tested in urine samples by D.F.E. and
subsequently in a clinical trial of urine samples submitted to
a NIDA certified laboratory. In both cases the laboratories used
EMIT II as their screening procedure. All positive samples by
either screening method were confirmed by GC/MS. The data was
combined and the results are summarized as follows:
| |
Syva
EMIT II Positive |
Syva
EMIT II Negative |
| DrugCheck
5 Positive |
188
|
1 |
| DrugCheck
5 Negative |
0
|
340 |
When compared to EMIT II the relative sensitivity
between positive samples was 100% . The relative specificity between
negative samples was 99.7%. The concordance of the combined data
with respect to EMIT II was 99.8%.
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| |
Syva
EMIT II Positive
|
Syva
EMIT II Negative
|
| DrugCheck
5 Positive |
297 |
4 |
| DrugCheck
5 Negative |
4
|
259 |
When compared to EMIT II the relative sensitivity
between positive samples was 98.67% . The relative specificity between
negative samples was 98.48%. The concordance of the combined data
with respect to EMIT II was 98.58%.
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| |
Syva
EMIT II Positive
|
Syva
EMIT II Negative
|
| DrugCheck
5 Positive |
194
|
1 |
| DrugCheck
5 Negative |
0 |
212 |
When compared to EMIT II the relative sensitivity
between positive samples was 100% . The relative specificity between
negative samples was 99.55%. The concordance of the combined data
with respect to EMIT II was 99.75%.
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| |
Syva
EMIT II Positive |
Syva
EMIT II Negative |
| DrugCheck
5 Positive |
172
|
0 |
| DrugCheck
5 Negative |
0
|
190 |
When compared to EMIT II the relative sensitivity
between positive samples was 100% . The relative specificity between
negative samples was 100%. The concordance of the combined data
with respect to EMIT II was 100%.
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| |
Syva
EMIT II Positive |
Syva
EMIT II Negative |
| DrugCheck
5 Positive |
179
|
14 |
| DrugCheck
5 Negative |
0
|
262
|
When compared to EMIT II the relative sensitivity
between positive samples was 100% . The relative specificity between
negative samples was 94.9%. The concordance of the combined data
with respect to EMIT II was 96.92%.
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1 (Table of Contents) - 2-3-4-5-6
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